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Langerhans cells

Noun

1. Dendritic cells (antigen-presenting immune cells) of the skin and mucosa, and contain large granules called Birbeck granules. They are present in all layers of the epidermis, but are most prominent in the stratum spinosum. They also occur in the papillary dermis, particularly around blood vessels, as well as in the mucosa of the mouth, foreskin, and vagina. They can be found in other tissues, such as lymph nodes, particularly in association with the condition Langerhans cell histiocytosis (LCH). (wikipedia.org)

2. Any of the dendritic cells of the interstitial spaces of the mammalian epidermis that appear rod- or racket-shaped and are similar to melanocytes but cannot oxidize phenols. (The American Heritage® Medical Dictionary)

See centroacinar cell.

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