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Islet of Langerhans

/ˈlaNGərˌhanz/  /ˈläNGərˌhäns/

Plural, islets of Langerhans

1. The regions of the pancreas that contain its endocrine (i.e., hormone-producing) cells. Discovered in 1869 by German pathological anatomist Paul Langerhans at the age of 22, the islets of Langerhans constitute approximately 1 to 2% of the mass of the pancreas. (

2. Regions in the pancreas that contain its endocrine cells (

3. Irregular clusters of endocrine cells scattered throughout the tissue of the pancreas that secrete insulin and glucagon. (

Syn: Islands of Langerhans, isles of Langerhans

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