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006 Donnan Equilibrium and Driving Force

Donnan Equilibrium? Driving Force? What in the world do those things mean? Well, you’re about to find out. In this video I explain the concept of Donnan equilibrium and show how that leads to the Driving Force that’s responsible for generating an Action Potential, otherwise known as the Nerve Impulse. If you want to know even more details about Donnan Equilibrium, check out my Notes on the Nervous System.

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Leslie Samuel is the creator of Interactive Biology. His mission is to use this site to Make Biology fun for people all over the world.

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72 Responses to “006 Donnan Equilibrium and Driving Force”

  1. mazas1991 August 22, 2010 at 5:40 am #

    nice work man.well done.it was well-organized.where can i fing the other episodes?

  2. mazas1991 August 22, 2010 at 5:49 am #

    And i was wondering.i am confused on smthing.What is the exact difference between Nerst equation Goldmans equation and Donnan equilibrium?because i dont understand clearly what each one talks about.thanx in advance.

  3. InteractiveBiology August 22, 2010 at 8:56 am #

    @mazas1991

    I will be working on more episodes pretty soon, but will be stepping back and starting with basic stuff.

    To answer your question, the Nernst equation is the formula used to calculate the Equilibrium potential for an individual ion (e.g. sodium).

    Donnan Equilibrium is similar to the Equilibrium potential.

    Goldman’s equation takes all of the ions into consideration and allows you to calculate the membrane potential of the neuron.

    Hope that helps!

    Leslie

  4. mazas1991 August 22, 2010 at 9:05 am #

    @InteractiveBiology thanx very much…yeap it did but i read so many stuff about it that i got confused a bit..if u can, leave an msn or fb or something so i can ask u online some questions that still confuse me..because i have an exam in 1 week so i would appreciate sooooooo much…so if u have time and will hit me up with a message or answer to this comment.thank you very very much in advance.

  5. mazas1991 August 22, 2010 at 9:05 am #

    thanx very much…yeap it did but i read so many stuff about it that i got confused a bit..if u can, leave an msn or fb or something so i can ask u online some questions that still confuse me..because i have an exam in 1 week so i would appreciate sooooooo much…so if u have time and will hit me up with a message or answer to this comment.thank you very very much in advance.

  6. InteractiveBiology August 22, 2010 at 9:15 am #

    @mazas1991 The best way to contact me is to use the link in the description of the video. It goes to my Interactive Biology website. There’s also a link to my facebook page on that site.

    All the best!

  7. InteractiveBiology August 22, 2010 at 9:15 am #

    The best way to contact me is to use the link in the description of the video. It goes to my Interactive Biology website. There’s also a link to my facebook page on that site.

    All the best!

  8. mazas1991 August 22, 2010 at 9:19 am #

    @InteractiveBiology i did it.is there anyway to talk via chat ? thanks

  9. mazas1991 August 22, 2010 at 9:19 am #

    i did it.is there anyway to talk via chat ? thanks

  10. InteractiveBiology August 22, 2010 at 9:27 am #

    @mazas1991 Yeah, depending on my time availability. Send me a message and we can go from there. I don’t post that info publicly on youtube for the fear of spam :)

  11. InteractiveBiology August 22, 2010 at 9:27 am #

    Yeah, depending on my time availability. Send me a message and we can go from there. I don’t post that info publicly on youtube for the fear of spam :)

  12. mazas1991 August 22, 2010 at 9:30 am #

    @InteractiveBiology yeah its better this way.could you send me a message so i can reply because i dont know how to do it plz :S

  13. mazas1991 August 22, 2010 at 9:30 am #

    yeah its better this way.could you send me a message so i can reply because i dont know how to do it plz :S

  14. InteractiveBiology August 22, 2010 at 9:38 am #

    @mazas1991 Like I said, send me a message from my website. Go to the site and click on the contact link. You can send any message from there

  15. InteractiveBiology August 22, 2010 at 9:38 am #

    Like I said, send me a message from my website. Go to the site and click on the contact link. You can send any message from there

  16. mazas1991 August 22, 2010 at 9:40 am #

    nice work man.well done.it was well-organized.where can i fing the other episodes?

  17. mazas1991 August 22, 2010 at 9:49 am #

    And i was wondering.i am confused on smthing.What is the exact difference between Nerst equation Goldmans equation and Donnan equilibrium?because i dont understand clearly what each one talks about.thanx in advance.

  18. mazas1991 August 22, 2010 at 9:51 am #

    @InteractiveBiology i posted in ur page on facebook.this is me.

  19. mazas1991 August 22, 2010 at 9:51 am #

    i posted in ur page on facebook.this is me.

  20. InteractiveBiology August 22, 2010 at 12:56 pm #

    @mazas1991

    I will be working on more episodes pretty soon, but will be stepping back and starting with basic stuff.

    To answer your question, the Nernst equation is the formula used to calculate the Equilibrium potential for an individual ion (e.g. sodium).

    Donnan Equilibrium is similar to the Equilibrium potential.

    Goldman’s equation takes all of the ions into consideration and allows you to calculate the membrane potential of the neuron.

    Hope that helps!

    Leslie

  21. mazas1991 August 22, 2010 at 1:05 pm #

    thanx very much…yeap it did but i read so many stuff about it that i got confused a bit..if u can, leave an msn or fb or something so i can ask u online some questions that still confuse me..because i have an exam in 1 week so i would appreciate sooooooo much…so if u have time and will hit me up with a message or answer to this comment.thank you very very much in advance.

  22. InteractiveBiology August 22, 2010 at 1:15 pm #

    The best way to contact me is to use the link in the description of the video. It goes to my Interactive Biology website. There’s also a link to my facebook page on that site.

    All the best!

  23. mazas1991 August 22, 2010 at 1:19 pm #

    i did it.is there anyway to talk via chat ? thanks

  24. InteractiveBiology August 22, 2010 at 1:27 pm #

    Yeah, depending on my time availability. Send me a message and we can go from there. I don’t post that info publicly on youtube for the fear of spam :)

  25. mazas1991 August 22, 2010 at 1:30 pm #

    yeah its better this way.could you send me a message so i can reply because i dont know how to do it plz :S

  26. InteractiveBiology August 22, 2010 at 1:38 pm #

    Like I said, send me a message from my website. Go to the site and click on the contact link. You can send any message from there

  27. mazas1991 August 22, 2010 at 1:51 pm #

    i posted in ur page on facebook.this is me.

  28. rohanaurora March 22, 2011 at 3:33 am #

    Its a lovely video with real life example given. Thumbs Up.

  29. InteractiveBiology March 22, 2011 at 6:07 am #

    @rohanaurora Thanks a bunch. Glad you are enjoying the videos. Stay subscribed for more :)

  30. InteractiveBiology March 22, 2011 at 6:07 am #

    Thanks a bunch. Glad you are enjoying the videos. Stay subscribed for more :)

  31. Rohan Aurora March 22, 2011 at 7:33 am #

    Its a lovely video with real life example given. Thumbs Up.

  32. Rohan Aurora March 22, 2011 at 7:33 am #

    Its a lovely video with real life example given. Thumbs Up.

  33. InteractiveBiology March 22, 2011 at 10:07 am #

    Thanks a bunch. Glad you are enjoying the videos. Stay subscribed for more :)

  34. Tapahtumahorisontti May 19, 2011 at 2:41 pm #

    Correct me if I’m wrong but should Donnan equilibrium require at least two permeable ions and one non-permeable anion on either side?

  35. Tapahtumahorisontti May 19, 2011 at 2:42 pm #

    Correct me if I’m wrong but shouldn’t Donnan equilibrium require at least two permeable ions and one non-permeable anion on either side?

  36. Tapahtumahorisontti May 19, 2011 at 6:42 pm #

    Correct me if I’m wrong but shouldn’t Donnan equilibrium require at least two permeable ions and one non-permeable anion on either side?

  37. InteractiveBiology May 19, 2011 at 7:56 pm #

    @Tapahtumahorisontti Not sure about that one.

  38. InteractiveBiology May 19, 2011 at 7:56 pm #

    Not sure about that one.

  39. InteractiveBiology May 19, 2011 at 11:56 pm #

    Not sure about that one.

  40. ediniz101 May 26, 2011 at 10:16 pm #

    isnt sodium moving into the cell because of concentration gradient? and its being stopped by its charge potential?

  41. ediniz101 May 27, 2011 at 2:16 am #

    isnt sodium moving into the cell because of concentration gradient? and its being stopped by its charge potential?

  42. InteractiveBiology May 27, 2011 at 3:19 pm #

    @ediniz101 Yes, that can happen depending on the conditions.

  43. InteractiveBiology May 27, 2011 at 3:19 pm #

    Yes, that can happen depending on the conditions.

  44. InteractiveBiology May 27, 2011 at 7:19 pm #

    Yes, that can happen depending on the conditions.

  45. selenaddict August 5, 2011 at 1:12 pm #

    Can someone explain me why we say that sodium is at is own equilibrium’??
    when we consider only K+ and Na+ we say that there s no equilibrium , coz we say that membrane potentiale isnt an equilibrium potential ..am i wrong??in fact in the membrane state of rest there s flow of Na+ trhought the membrane to the inner surface of the membrane..

  46. InteractiveBiology August 5, 2011 at 1:14 pm #

    @selenaddict The statement I think I made was that the Membrane potential is at the Equilibrium potential for Sodium. Not 100% sure what you are asking though.

  47. InteractiveBiology August 5, 2011 at 1:14 pm #

    The statement I think I made was that the Membrane potential is at the Equilibrium potential for Sodium. Not 100% sure what you are asking though.

  48. selenaddict August 5, 2011 at 5:12 pm #

    Can someone explain me why we say that sodium is at is own equilibrium’??
    when we consider only K+ and Na+ we say that there s no equilibrium , coz we say that membrane potentiale isnt an equilibrium potential ..am i wrong??in fact in the membrane state of rest there s flow of Na+ trhought the membrane to the inner surface of the membrane..

  49. InteractiveBiology August 5, 2011 at 5:14 pm #

    The statement I think I made was that the Membrane potential is at the Equilibrium potential for Sodium. Not 100% sure what you are asking though.

  50. aboylikeyou88 September 11, 2011 at 4:14 am #

    very useful video…thanks

  51. InteractiveBiology September 11, 2011 at 7:59 am #

    @aboylikeyou88 You are very much welcome!

  52. InteractiveBiology September 11, 2011 at 7:59 am #

    You are very much welcome!

  53. InteractiveBiology September 11, 2011 at 11:59 am #

    You are very much welcome!

  54. Praw48 September 15, 2011 at 8:21 pm #

    TERRIBLE puns XD but a really helpful video. Thank you :)

  55. InteractiveBiology September 15, 2011 at 8:39 pm #

    @Praw48 LOL, terrible puns are the best puns ;)

  56. InteractiveBiology September 15, 2011 at 8:39 pm #

    LOL, terrible puns are the best puns ;)

  57. Praw48 September 16, 2011 at 12:21 am #

    TERRIBLE puns XD but a really helpful video. Thank you :)

  58. InteractiveBiology September 16, 2011 at 12:39 am #

    LOL, terrible puns are the best puns ;)

  59. zackboomer September 18, 2011 at 5:52 pm #

    love the style of your vids

  60. zackboomer September 18, 2011 at 9:52 pm #

    love the style of your vids

  61. Dosiyev March 8, 2012 at 5:39 pm #

    Bad video …some mistakes

  62. Dosiyev March 8, 2012 at 5:39 pm #

    Bad video …some mistakes

  63. Dosiyev March 8, 2012 at 10:39 pm #

    Bad video …some mistakes

  64. Neil April 19, 2012 at 2:48 am #

    What is Actin and Myosin in simple language? What are their roles and uses in our body especially muscle?

  65. Lana April 24, 2012 at 9:39 am #

    You mentioned that the Na+ needs to reach a donnan equilibrium of 58MV, and when it is not near the resting membrane potential state of -50 to -80MV, the NA+ feels uncomfortable. Thus, causing sodium ions to rush into the cell. However, how does rushing into the cell make it “positive?” I thought the point of sodium to move into the cell was to become more comfortable, which meant reaching -50 to -80MV?

    Thank you in advance!

  66. bdemare00 May 8, 2012 at 1:04 pm #

    for questions about the define 58mV, look at the netnst equation ;)

  67. bdemare00 May 8, 2012 at 1:04 pm #

    for questions about the define 58mV, look at the netnst equation ;)

  68. RuthmcEvoy June 23, 2012 at 7:28 pm #

    such a happy video !
    the visuals really help me to remember the facts ! . Thank you for making them :D !

  69. RuthmcEvoy June 23, 2012 at 7:28 pm #

    such a happy video !
    the visuals really help me to remember the facts ! . Thank you for making them :D !

  70. Daniela P September 11, 2013 at 1:58 am #

    Thank you! Your excellent!

  71. MUKHLESUR RAHMAN January 29, 2014 at 4:39 am #

    Sir you are really awasum….Salute to u…Thnx for ur great help….