004 Ion Channels: The Proteins in the Membrane of Neurons


There are 4 important classes of proteins in the membrane of neurons: Passive/Leakage ion channels, Sodium-Potassium pumps, Voltage-gated ion channels, and Ligand-gated ion channels. In order to understand how the neurons functions, we have to understand how those channels work. Watch the following video to learn about these proteins.

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38 Comments
  1. WOW this was great for my Anatomy class!!

  2. Glad you guys are finding value in it. All the best and stay tuned for more :)

  3. this is the best :)

  4. WOW I love this video, he makes it so much easier to understand!!!
    He needs to be my instructor

  5. :) thanks!! very helpful!

  6. Thank you for producing such great videos. I discovered them just this week while trying to find some “fun” animations for our Neurodiagnostic students. We are watching them in the classroom and then they watch again at home. This is exactly the kind of teaching aid we need for today’s students.

    • Hi Riki,

      That’s very exciting to hear. It’s good to know that the content I’m producing is being used to help students in different parts of the world and in different ways. Thanks for helping to spread the word by sharing it with your students, and all the best with your class.

  7. i love expanding my mind when i’m high, great vid

  8. @dimabbq Wow. Hey, learning is fun even when you aren’t high :D

  9. Thanks! What about Mechanically regulated channels and chemically gated channels? (How many channels are there?)

  10. @Rathanasan I have examples of those in some of the other episodes. Check out my channel and search for the following titles:

    The Role of Hair Cells in Hearing – Episode 40 (Examples of Mechanically regulated)
    Two Types of Receptors – Episode 17 (Examples of chemically gated)

    The number of channels vary from neuron to neuron so I can’t give a definite answer to that. Stay tuned for more videos :)

  11. @Rathanasan I have examples of those in some of the other episodes. Check out my channel and search for the following titles:

    The Role of Hair Cells in Hearing – Episode 40 (Examples of Mechanically regulated)
    Two Types of Receptors – Episode 17 (Examples of chemically gated)

    The number of channels vary from neuron to neuron so I can’t give a definite answer to that. Stay tuned for more videos :)

  12. What happens at 3:50 does phosphate add to ADP and become ATP? Or is it the other way around so it consumes phosphate?

  13. @Lcakaelsie ATP is USED by the Na/K pump, and that involves ATP being broken down to ADP and an inorganic phosphate. That gives the pump energy to move the NA+ and K+ against the concentration gradient. Hope that helps! All the best!

    • Oh. I realized after posting just now that you may have actually answered my question with this comment.

      • Awesome Scott.

        Glad to know I was able to answer your question without thinking :)

        Hope you continue to find value in the content.

  14. I love this channel too! Thanks Leslie for making A&P easier to understand. More power! I’m your fan!

  15. @MyBestString1 You are very much welcome :)

    Glad you are finding the videos useful!

  16. On the video homepage, I couldn’t find video 003. I see all the others. Did it get taken down? Thanks. :)

    • You know what, I never put it on that page. My bad. I just added it. Unfortunately, that page sorts the categories alphabetically, so that one shows up at the top, but you can see it now.

  17. @InteractiveBiology the two do go well together i find

  18. Great video, very helpful!

  19. Great video, very helpful!

  20. @diamond61789 Thank you. Glad to help!

  21. i dont really understand volted gated ion channels :O can you explain please! thanks!

  22. @fazieeBEE Try watching the video multiple times. I don’t think I could explain it better in the comments than it’s explained in the video.

  23. this all seems pretty ungodly to me…

  24. you are my savior leslie.. !!! ur vids are great.. mwahkss

  25. @mprcb28 Glad to be able to help. All the best!

  26. I swear you deserve A NOBEL PRIZE FOR THESE VIDEOS OF YOURS :)

  27. @zai4booc That would be an honor for Leslie, LOL! Thank you for watching. Glad you’re finding value in them. Stay tuned for more :)

  28. I learn more in this 6 min video then a week for my bio teacher

  29. @justin505k Wow! That’s so nice to hear :) Glad that we’re able to help. Thank you! Stay tuned. We have more Biology videos coming very soon :)

  30. THAAAAANK YOUUUUUUUUUUUUUUUUU!!!!!!!!!!

  31. @xamandaxgatewayx You’re veeeerrrry welcome :) Keep on coming back for more new Biology video uploads.

  32. Hey :) Which cell membrane was the diagram referring to, is it a cell of the skin, or a nerve or something else?

  33. tx very much for the great vids// very easy to understand

  34. Hello! I’ve just begun listening to these episodes. Every single video has been clear, concise, and truly the best introduction-to-neuroscience series I’ve encountered yet. I’m going back through several of the videos again, from the beginning, and now that I’m going back through I’d like to ask a few questions, if you are still available for commenting on some of these earliest videos?

    Anyway:
    In this episode, you spend some moments talking about the Sodium-Potassium. I am curious how this process actually works. How is it that something like a “Sodium-Potassium” pump can exist? I don’t understand the process behind a biological structure being somehow able to distinguish between sodium and potassium? Why is it pumping? Also, how is…/motion/ happening? Does this require energy? and more ATP?

    Again, I should say that I am not at /all/ a neuroscience or biology student, so perhaps these questions are very trivial. But I am very interested in all of this. Fantastic series.

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