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004 Ion Channels: The Proteins in the Membrane of Neurons

There are 4 important classes of proteins in the membrane of neurons: Passive/Leakage ion channels, Sodium-Potassium pumps, Voltage-gated ion channels, and Ligand-gated ion channels. In order to understand how the neurons functions, we have to understand how those channels work. Watch the following video to learn about these proteins.

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Leslie Samuel is the creator of Interactive Biology. His mission is to use this site to Make Biology fun for people all over the world.

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100 Responses to “004 Ion Channels: The Proteins in the Membrane of Neurons”

  1. tabarca76 October 16, 2010 at 7:10 am #

    Good job Leslie!

  2. PlethoraXofXThoughts October 31, 2010 at 7:16 pm #

    Great video. Very clear and concise…unlike my current neurobiology
    teacher -.-

  3. 1shikela November 15, 2010 at 7:36 pm #

    WOW this was great for my Anatomy class!!

  4. InteractiveBiology November 15, 2010 at 7:43 pm #

    Glad you guys are finding value in it. All the best and stay tuned for more :)

  5. InteractiveBiology November 15, 2010 at 7:43 pm #

    Glad you guys are finding value in it. All the best and stay tuned for more :)

  6. vtabano December 14, 2010 at 2:17 pm #

    this is the best :)

  7. raenmaxi January 6, 2011 at 9:28 pm #

    WOW I love this video, he makes it so much easier to understand!!!
    He needs to be my instructor

  8. raenmaxi January 6, 2011 at 9:28 pm #

    WOW I love this video, he makes it so much easier to understand!!! He needs
    to be my instructor

  9. oncrack87 February 1, 2011 at 1:13 am #

    :) thanks!! very helpful!

  10. Cmaxon08 February 1, 2011 at 1:13 am #

    :) thanks!! very helpful!

  11. Riki February 24, 2011 at 6:49 pm #

    Thank you for producing such great videos. I discovered them just this week while trying to find some “fun” animations for our Neurodiagnostic students. We are watching them in the classroom and then they watch again at home. This is exactly the kind of teaching aid we need for today’s students.

    • Leslie February 24, 2011 at 8:04 pm #

      Hi Riki,

      That’s very exciting to hear. It’s good to know that the content I’m producing is being used to help students in different parts of the world and in different ways. Thanks for helping to spread the word by sharing it with your students, and all the best with your class.

  12. dimabbq March 17, 2011 at 9:57 pm #

    i love expanding my mind when i’m high, great vid

  13. Dima March 17, 2011 at 9:57 pm #

    i love expanding my mind when i’m high, great vid

  14. InteractiveBiology March 17, 2011 at 10:15 pm #

    @dimabbq Wow. Hey, learning is fun even when you aren’t high :D

  15. Rathanasan March 22, 2011 at 3:03 am #

    Thanks! What about Mechanically regulated channels and chemically gated channels? (How many channels are there?)

  16. Rathana San March 22, 2011 at 3:03 am #

    Thanks! What about Mechanically regulated channels and chemically gated
    channels? (How many channels are there?)

  17. InteractiveBiology March 22, 2011 at 6:06 am #

    @Rathanasan I have examples of those in some of the other episodes. Check out my channel and search for the following titles:

    The Role of Hair Cells in Hearing – Episode 40 (Examples of Mechanically regulated)
    Two Types of Receptors – Episode 17 (Examples of chemically gated)

    The number of channels vary from neuron to neuron so I can’t give a definite answer to that. Stay tuned for more videos :)

  18. InteractiveBiology March 22, 2011 at 6:06 am #

    @Rathanasan I have examples of those in some of the other episodes. Check out my channel and search for the following titles:

    The Role of Hair Cells in Hearing – Episode 40 (Examples of Mechanically regulated)
    Two Types of Receptors – Episode 17 (Examples of chemically gated)

    The number of channels vary from neuron to neuron so I can’t give a definite answer to that. Stay tuned for more videos :)

  19. InteractiveBiology March 22, 2011 at 6:06 am #

    I have examples of those in some of the other episodes. Check out my channel and search for the following titles:

    The Role of Hair Cells in Hearing – Episode 40 (Examples of Mechanically regulated)
    Two Types of Receptors – Episode 17 (Examples of chemically gated)

    The number of channels vary from neuron to neuron so I can’t give a definite answer to that. Stay tuned for more videos :)

  20. InteractiveBiology March 22, 2011 at 6:06 am #

    I have examples of those in some of the other episodes. Check out my channel and search for the following titles:

    The Role of Hair Cells in Hearing – Episode 40 (Examples of Mechanically regulated)
    Two Types of Receptors – Episode 17 (Examples of chemically gated)

    The number of channels vary from neuron to neuron so I can’t give a definite answer to that. Stay tuned for more videos :)

  21. Lcakaelsie April 21, 2011 at 12:29 am #

    What happens at 3:50 does phosphate add to ADP and become ATP? Or is it the other way around so it consumes phosphate?

  22. InteractiveBiology April 21, 2011 at 3:00 pm #

    @Lcakaelsie ATP is USED by the Na/K pump, and that involves ATP being broken down to ADP and an inorganic phosphate. That gives the pump energy to move the NA+ and K+ against the concentration gradient. Hope that helps! All the best!

    • Scott February 2, 2012 at 4:37 pm #

      Oh. I realized after posting just now that you may have actually answered my question with this comment.

      • Leslie Samuel February 2, 2012 at 9:09 pm #

        Awesome Scott.

        Glad to know I was able to answer your question without thinking :)

        Hope you continue to find value in the content.

  23. InteractiveBiology April 21, 2011 at 3:00 pm #

    ATP is USED by the Na/K pump, and that involves ATP being broken down to ADP and an inorganic phosphate. That gives the pump energy to move the NA+ and K+ against the concentration gradient. Hope that helps! All the best!

  24. InteractiveBiology April 21, 2011 at 3:00 pm #

    @Lcakaelsie ATP is USED by the Na/K pump, and that involves ATP being
    broken down to ADP and an inorganic phosphate. That gives the pump energy
    to move the NA+ and K+ against the concentration gradient. Hope that helps!
    All the best!

  25. MyBestString1 April 26, 2011 at 11:51 pm #

    I love this channel too! Thanks Leslie for making A&P easier to understand. More power! I’m your fan!

  26. InteractiveBiology April 26, 2011 at 11:53 pm #

    You are very much welcome :)

    Glad you are finding the videos useful!

  27. InteractiveBiology April 26, 2011 at 11:53 pm #

    @MyBestString1 You are very much welcome :)

    Glad you are finding the videos useful!

  28. MyBestString1 April 27, 2011 at 3:51 am #

    I love this channel too! Thanks Leslie for making A&P easier to understand. More power! I’m your fan!

  29. InteractiveBiology April 27, 2011 at 3:53 am #

    You are very much welcome :)

    Glad you are finding the videos useful!

  30. Everett June 1, 2011 at 7:18 pm #

    On the video homepage, I couldn’t find video 003. I see all the others. Did it get taken down? Thanks. :)

    • Lrsamuel June 3, 2011 at 3:01 pm #

      You know what, I never put it on that page. My bad. I just added it. Unfortunately, that page sorts the categories alphabetically, so that one shows up at the top, but you can see it now.

  31. dimabbq July 3, 2011 at 12:17 am #

    the two do go well together i find

  32. dimabbq July 3, 2011 at 12:17 am #

    @InteractiveBiology the two do go well together i find

  33. dimabbq July 3, 2011 at 4:17 am #

    the two do go well together i find

  34. diamond61789 July 25, 2011 at 12:46 am #

    Great video, very helpful!

  35. diamond61789 July 25, 2011 at 12:46 am #

    Great video, very helpful!

  36. diamond61789 July 25, 2011 at 4:46 am #

    Great video, very helpful!

  37. InteractiveBiology July 25, 2011 at 9:44 am #

    Thank you. Glad to help!

  38. InteractiveBiology July 25, 2011 at 9:44 am #

    @diamond61789 Thank you. Glad to help!

  39. InteractiveBiology July 25, 2011 at 1:44 pm #

    Thank you. Glad to help!

  40. fazieeBEE September 1, 2011 at 11:38 pm #

    i dont really understand volted gated ion channels :O can you explain please! thanks!

  41. fazieeBEE September 2, 2011 at 3:38 am #

    i dont really understand volted gated ion channels :O can you explain please! thanks!

  42. InteractiveBiology September 2, 2011 at 7:47 am #

    Try watching the video multiple times. I don’t think I could explain it better in the comments than it’s explained in the video.

  43. InteractiveBiology September 2, 2011 at 7:47 am #

    @fazieeBEE Try watching the video multiple times. I don’t think I could explain it better in the comments than it’s explained in the video.

  44. InteractiveBiology September 2, 2011 at 11:47 am #

    Try watching the video multiple times. I don’t think I could explain it better in the comments than it’s explained in the video.

  45. waksibra September 13, 2011 at 4:43 am #

    this all seems pretty ungodly to me…

  46. waksibra September 13, 2011 at 8:43 am #

    this all seems pretty ungodly to me…

  47. mprcb28 October 8, 2011 at 7:36 pm #

    you are my savior leslie.. !!! ur vids are great.. mwahkss

  48. mprcb28 October 8, 2011 at 11:36 pm #

    you are my savior leslie.. !!! ur vids are great.. mwahkss

  49. InteractiveBiology October 9, 2011 at 10:09 am #

    Glad to be able to help. All the best!

  50. InteractiveBiology October 9, 2011 at 10:09 am #

    @mprcb28 Glad to be able to help. All the best!

  51. InteractiveBiology October 9, 2011 at 2:09 pm #

    Glad to be able to help. All the best!

  52. zai4booc November 27, 2011 at 9:00 am #

    I swear you deserve A NOBEL PRIZE FOR THESE VIDEOS OF YOURS :)

  53. zai4booc November 27, 2011 at 2:00 pm #

    I swear you deserve A NOBEL PRIZE FOR THESE VIDEOS OF YOURS :)

  54. InteractiveBiology November 27, 2011 at 10:13 pm #

    That would be an honor for Leslie, LOL! Thank you for watching. Glad you’re finding value in them. Stay tuned for more :)

  55. InteractiveBiology November 27, 2011 at 10:13 pm #

    @zai4booc That would be an honor for Leslie, LOL! Thank you for watching. Glad you’re finding value in them. Stay tuned for more :)

  56. InteractiveBiology November 28, 2011 at 3:13 am #

    That would be an honor for Leslie, LOL! Thank you for watching. Glad you’re finding value in them. Stay tuned for more :)

  57. justin505k December 5, 2011 at 6:58 pm #

    I learn more in this 6 min video then a week for my bio teacher

  58. justin505k December 5, 2011 at 11:58 pm #

    I learn more in this 6 min video then a week for my bio teacher

  59. InteractiveBiology December 6, 2011 at 9:54 am #

    Wow! That’s so nice to hear :) Glad that we’re able to help. Thank you! Stay tuned. We have more Biology videos coming very soon :)

  60. InteractiveBiology December 6, 2011 at 9:54 am #

    @justin505k Wow! That’s so nice to hear :) Glad that we’re able to help. Thank you! Stay tuned. We have more Biology videos coming very soon :)

  61. InteractiveBiology December 6, 2011 at 2:54 pm #

    Wow! That’s so nice to hear :) Glad that we’re able to help. Thank you! Stay tuned. We have more Biology videos coming very soon :)

  62. xamandaxgatewayx December 24, 2011 at 10:22 am #

    THAAAAANK YOUUUUUUUUUUUUUUUUU!!!!!!!!!!

  63. xamandaxgatewayx December 24, 2011 at 3:22 pm #

    THAAAAANK YOUUUUUUUUUUUUUUUUU!!!!!!!!!!

  64. InteractiveBiology December 25, 2011 at 11:13 pm #

    @xamandaxgatewayx You’re veeeerrrry welcome :) Keep on coming back for more new Biology video uploads.

  65. InteractiveBiology December 25, 2011 at 11:13 pm #

    You’re veeeerrrry welcome :) Keep on coming back for more new Biology video uploads.

  66. InteractiveBiology December 26, 2011 at 4:13 am #

    You’re veeeerrrry welcome :) Keep on coming back for more new Biology video uploads.

  67. RoxasX58 December 29, 2011 at 12:47 pm #

    Hey :) Which cell membrane was the diagram referring to, is it a cell of the skin, or a nerve or something else?

  68. RoxasX58 December 29, 2011 at 5:47 pm #

    Hey :) Which cell membrane was the diagram referring to, is it a cell of the skin, or a nerve or something else?

  69. TheHeartmedia January 2, 2012 at 2:38 am #

    tx very much for the great vids// very easy to understand

  70. TheHeartmedia January 2, 2012 at 7:38 am #

    tx very much for the great vids// very easy to understand

  71. Scott February 2, 2012 at 4:26 pm #

    Hello! I’ve just begun listening to these episodes. Every single video has been clear, concise, and truly the best introduction-to-neuroscience series I’ve encountered yet. I’m going back through several of the videos again, from the beginning, and now that I’m going back through I’d like to ask a few questions, if you are still available for commenting on some of these earliest videos?

    Anyway:
    In this episode, you spend some moments talking about the Sodium-Potassium. I am curious how this process actually works. How is it that something like a “Sodium-Potassium” pump can exist? I don’t understand the process behind a biological structure being somehow able to distinguish between sodium and potassium? Why is it pumping? Also, how is…/motion/ happening? Does this require energy? and more ATP?

    Again, I should say that I am not at /all/ a neuroscience or biology student, so perhaps these questions are very trivial. But I am very interested in all of this. Fantastic series.

  72. bs0u31c3 March 4, 2012 at 1:12 pm #

    Lectures in college are terrible. I learn more in a 10minute video than the whole year in college something is not right I am basically paying tuition fees to write exams because I learn nothing. Thank God for great online teachers like you. Sighs

  73. bs0u31c3 March 4, 2012 at 6:12 pm #

    Lectures in college are terrible. I learn more in a 10minute video than the whole year in college something is not right I am basically paying tuition fees to write exams because I learn nothing. Thank God for great online teachers like you. Sighs

  74. GoldenPhoenix1981 March 8, 2012 at 8:38 pm #

    Is it right to believe that the passive ion channels are a form of diffusion?

  75. GoldenPhoenix1981 March 9, 2012 at 1:38 am #

    Is it right to believe that the passive ion channels are a form of diffusion?

  76. lynexeye March 17, 2012 at 2:23 pm #

    Just like everybody, I would love to say too that Thank you so much. You are so helpful and easy to understand. Love your Videos… Please Upload more Videos about Different other Parts/Organs of the Body… Keep looking for your incoming videos..Loves and Regards from Pakistan <3

  77. 10eighths March 21, 2012 at 9:52 pm #

    how would you expect the strength of an electric current across an ion channel to compare with the strength of across an ion pump?

  78. 10eighths March 22, 2012 at 1:52 am #

    how would you expect the strength of an electric current across an ion channel to compare with the strength of across an ion pump?

  79. daknownunknown1 April 8, 2012 at 3:01 am #

    Thanks you so much. These video’s are really helping me to break down what I have read in school and puts a more entertaining view/spin on it. Your videos are of the best I have seen. You are helping me to pass my major exam coming up in June. Thanks again!!!!!

  80. daknownunknown1 April 8, 2012 at 7:01 am #

    Thanks you so much. These video’s are really helping me to break down what I have read in school and puts a more entertaining view/spin on it. Your videos are of the best I have seen. You are helping me to pass my major exam coming up in June. Thanks again!!!!!

  81. MsMsQt April 12, 2012 at 12:05 am #

    How cool was that=) thank you much

  82. MsMsQt April 12, 2012 at 4:05 am #

    How cool was that=) thank you much

  83. DerroQamishlo May 14, 2012 at 6:16 pm #

    Thank you so much! But I want to share some positive critic with you, I think you should lower the music volume a tiny bit, because I am more interested in hearing your voice than the music :)

    Keep up the work!

  84. DerroQamishlo May 14, 2012 at 6:16 pm #

    Thank you so much! But I want to share some positive critic with you, I think you should lower the music volume a tiny bit, because I am more interested in hearing your voice than the music :)

    Keep up the work!

  85. baysidefes August 23, 2012 at 5:58 pm #

    hi there, great video, i was wondering if you had any video that talks about chloride ion , and the chloride ion channels, and what can happen if the chloride ion is not able to pass out of the cell membrane

  86. hopkin104 August 25, 2012 at 8:04 pm #

    whats the difference between ion channels and facilitated channels?

  87. RidleyE August 27, 2012 at 9:57 pm #

    awesome music

  88. amodm10 October 2, 2012 at 12:08 am #

    you just saved my life.. from the bottom of my heart THANKS

  89. Leydi Roman March 11, 2013 at 12:10 am #

    you are great im been taking bio classes but I never had a prof capable of explaining this information. They have not clue what they lecture.

  90. ITouchHot March 17, 2013 at 9:25 pm #

    Tell me about it! Don’t you hate when you pay so much money for university classes and than end up learning from various sources like youtube, or random lectures on-line??

  91. Anthony Chao May 7, 2013 at 4:28 am #

    Amen…this is so true.

  92. royan rosche August 13, 2013 at 5:44 pm #

    Thanks for the video, what I am hearing is that an artificial neuron made of non biological material will not need the complex process that comes with the 4 proteins

  93. royan rosche August 13, 2013 at 5:44 pm #

    Thanks for the video, what I am hearing is that an artificial neuron made of non biological material will not need the complex process that comes with the 4 proteins

  94. royan rosche August 13, 2013 at 5:44 pm #

    ya?

  95. royan rosche August 13, 2013 at 5:44 pm #

    ya?

  96. Aine A August 14, 2013 at 1:27 pm #

    I wish you were my lecturer!!