004 Ion Channels: The Proteins in the Membrane of Neurons

There are 4 important classes of proteins in the membrane of neurons: Passive/Leakage ion channels, Sodium-Potassium pumps, Voltage-gated ion channels, and Ligand-gated ion channels. In order to understand how the neurons functions, we have to understand how those channels work. Watch the following video to learn about these proteins.



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  1. Great video. Very clear and concise…unlike my current neurobiology
    teacher -.-

  2. Glad you guys are finding value in it. All the best and stay tuned for more
    🙂

  3. WOW I love this video, he makes it so much easier to understand!!! He needs
    to be my instructor

  4. Thank you for producing such great videos. I discovered them just this week while trying to find some “fun” animations for our Neurodiagnostic students. We are watching them in the classroom and then they watch again at home. This is exactly the kind of teaching aid we need for today’s students.

  5. Hi Riki,

    That’s very exciting to hear. It’s good to know that the content I’m producing is being used to help students in different parts of the world and in different ways. Thanks for helping to spread the word by sharing it with your students, and all the best with your class.

  6. Thanks! What about Mechanically regulated channels and chemically gated
    channels? (How many channels are there?)

  7. @Rathanasan I have examples of those in some of the other episodes. Check out my channel and search for the following titles:

    The Role of Hair Cells in Hearing – Episode 40 (Examples of Mechanically regulated)
    Two Types of Receptors – Episode 17 (Examples of chemically gated)

    The number of channels vary from neuron to neuron so I can’t give a definite answer to that. Stay tuned for more videos 🙂

  8. @Rathanasan I have examples of those in some of the other episodes. Check out my channel and search for the following titles:

    The Role of Hair Cells in Hearing – Episode 40 (Examples of Mechanically regulated)
    Two Types of Receptors – Episode 17 (Examples of chemically gated)

    The number of channels vary from neuron to neuron so I can’t give a definite answer to that. Stay tuned for more videos 🙂

  9. I have examples of those in some of the other episodes. Check out my channel and search for the following titles:

    The Role of Hair Cells in Hearing – Episode 40 (Examples of Mechanically regulated)
    Two Types of Receptors – Episode 17 (Examples of chemically gated)

    The number of channels vary from neuron to neuron so I can’t give a definite answer to that. Stay tuned for more videos 🙂

  10. I have examples of those in some of the other episodes. Check out my channel and search for the following titles:

    The Role of Hair Cells in Hearing – Episode 40 (Examples of Mechanically regulated)
    Two Types of Receptors – Episode 17 (Examples of chemically gated)

    The number of channels vary from neuron to neuron so I can’t give a definite answer to that. Stay tuned for more videos 🙂

  11. @Lcakaelsie ATP is USED by the Na/K pump, and that involves ATP being broken down to ADP and an inorganic phosphate. That gives the pump energy to move the NA+ and K+ against the concentration gradient. Hope that helps! All the best!

  12. ATP is USED by the Na/K pump, and that involves ATP being broken down to ADP and an inorganic phosphate. That gives the pump energy to move the NA+ and K+ against the concentration gradient. Hope that helps! All the best!

  13. @Lcakaelsie ATP is USED by the Na/K pump, and that involves ATP being
    broken down to ADP and an inorganic phosphate. That gives the pump energy
    to move the NA+ and K+ against the concentration gradient. Hope that helps!
    All the best!

  14. I love this channel too! Thanks Leslie for making A&P easier to understand. More power! I’m your fan!

  15. You are very much welcome 🙂

    Glad you are finding the videos useful!

  16. On the video homepage, I couldn’t find video 003. I see all the others. Did it get taken down? Thanks. 🙂

  17. You know what, I never put it on that page. My bad. I just added it. Unfortunately, that page sorts the categories alphabetically, so that one shows up at the top, but you can see it now.

  18. Try watching the video multiple times. I don’t think I could explain it better in the comments than it’s explained in the video.

  19. That would be an honor for Leslie, LOL! Thank you for watching. Glad you’re finding value in them. Stay tuned for more 🙂

  20. Wow! That’s so nice to hear 🙂 Glad that we’re able to help. Thank you! Stay tuned. We have more Biology videos coming very soon 🙂

  21. You’re veeeerrrry welcome 🙂 Keep on coming back for more new Biology video uploads.

  22. Hey 🙂 Which cell membrane was the diagram referring to, is it a cell of the skin, or a nerve or something else?

  23. Hello! I’ve just begun listening to these episodes. Every single video has been clear, concise, and truly the best introduction-to-neuroscience series I’ve encountered yet. I’m going back through several of the videos again, from the beginning, and now that I’m going back through I’d like to ask a few questions, if you are still available for commenting on some of these earliest videos?

    Anyway:
    In this episode, you spend some moments talking about the Sodium-Potassium. I am curious how this process actually works. How is it that something like a “Sodium-Potassium” pump can exist? I don’t understand the process behind a biological structure being somehow able to distinguish between sodium and potassium? Why is it pumping? Also, how is…/motion/ happening? Does this require energy? and more ATP?

    Again, I should say that I am not at /all/ a neuroscience or biology student, so perhaps these questions are very trivial. But I am very interested in all of this. Fantastic series.

  24. Lectures in college are terrible. I learn more in a 10minute video than the whole year in college something is not right I am basically paying tuition fees to write exams because I learn nothing. Thank God for great online teachers like you. Sighs

  25. Lectures in college are terrible. I learn more in a 10minute video than the whole year in college something is not right I am basically paying tuition fees to write exams because I learn nothing. Thank God for great online teachers like you. Sighs

  26. Is it right to believe that the passive ion channels are a form of diffusion?

  27. Just like everybody, I would love to say too that Thank you so much. You are so helpful and easy to understand. Love your Videos… Please Upload more Videos about Different other Parts/Organs of the Body… Keep looking for your incoming videos..Loves and Regards from Pakistan <3

  28. how would you expect the strength of an electric current across an ion channel to compare with the strength of across an ion pump?

  29. how would you expect the strength of an electric current across an ion channel to compare with the strength of across an ion pump?

  30. Thanks you so much. These video’s are really helping me to break down what I have read in school and puts a more entertaining view/spin on it. Your videos are of the best I have seen. You are helping me to pass my major exam coming up in June. Thanks again!!!!!

  31. Thanks you so much. These video’s are really helping me to break down what I have read in school and puts a more entertaining view/spin on it. Your videos are of the best I have seen. You are helping me to pass my major exam coming up in June. Thanks again!!!!!

  32. Thank you so much! But I want to share some positive critic with you, I think you should lower the music volume a tiny bit, because I am more interested in hearing your voice than the music 🙂

    Keep up the work!

  33. Thank you so much! But I want to share some positive critic with you, I think you should lower the music volume a tiny bit, because I am more interested in hearing your voice than the music 🙂

    Keep up the work!

  34. hi there, great video, i was wondering if you had any video that talks about chloride ion , and the chloride ion channels, and what can happen if the chloride ion is not able to pass out of the cell membrane

  35. you are great im been taking bio classes but I never had a prof capable of explaining this information. They have not clue what they lecture.

  36. Tell me about it! Don’t you hate when you pay so much money for university classes and than end up learning from various sources like youtube, or random lectures on-line??

  37. Thanks for the video, what I am hearing is that an artificial neuron made of non biological material will not need the complex process that comes with the 4 proteins

  38. Thanks for the video, what I am hearing is that an artificial neuron made of non biological material will not need the complex process that comes with the 4 proteins

  39. Great stuff! Clear and concise, and great visuals.
    Thank you for your wonderful service.
    Will help me teach non-neurobiologists, neurophysiology.

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